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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: TERT All Species: 39.09
Human Site: T939 Identified Species: 71.67
UniProt: O14746 Number Species: 12
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens O14746 NP_937983.2 1132 126997 T939 G L L L D T R T L E V Q S D Y
Chimpanzee Pan troglodytes XP_001141663 1135 126922 T942 G L L L D T R T L E V Q S D Y
Rhesus Macaque Macaca mulatta XP_001096904 1132 126842 T939 G L L L D T R T L E V Q S D Y
Dog Lupus familis XP_851664 1092 121456 Q911 L G S A A P L Q L P A H C L F
Cat Felis silvestris
Mouse Mus musculus O70372 1122 127960 T932 G L L L D T Q T L E V F C D Y
Rat Rattus norvegicus Q673L6 1125 126915 T932 G L L L D T R T L E V F C D Y
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus NP_001026178 1346 155264 T1153 G L L L D V Q T L E V Y C D Y
Frog Xenopus laevis NP_001079102 1191 137998 T998 G L L L D T Q T L D V Y Y D Y
Zebra Danio Brachydanio rerio NP_001077335 1098 125968 T907 G L M I H T H T L D V Y K D Y
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_781093 1312 150053 T1118 G I V F K T Q T L N I S N D Y
Poplar Tree Populus trichocarpa
Maize Zea mays NP_001105870 1188 135970 T1000 G L L I N C E T L E I Q A D Y
Rice Oryza sativa
Thale Cress Arabidopsis thaliana NP_197187 1123 130561 T933 G L L I N S R T F E V Q V D Y
Baker's Yeast Sacchar. cerevisiae Q06163 884 102645 A707 A N R D K I L A V S S Q S D D
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 97.1 95.8 70.3 N.A. 63.3 63.3 N.A. N.A. 45.2 42.9 32.8 N.A. N.A. N.A. N.A. 27
Protein Similarity: 100 97.9 97.4 77.5 N.A. 74 73.5 N.A. N.A. 58.2 60.1 50.8 N.A. N.A. N.A. N.A. 42
P-Site Identity: 100 100 100 6.6 N.A. 80 86.6 N.A. N.A. 73.3 73.3 53.3 N.A. N.A. N.A. N.A. 40
P-Site Similarity: 100 100 100 13.3 N.A. 86.6 86.6 N.A. N.A. 80 86.6 73.3 N.A. N.A. N.A. N.A. 73.3
Percent
Protein Identity: N.A. 24.7 N.A. 24.8 20.7 N.A.
Protein Similarity: N.A. 40.4 N.A. 42.6 36.9 N.A.
P-Site Identity: N.A. 60 N.A. 66.6 20 N.A.
P-Site Similarity: N.A. 86.6 N.A. 86.6 26.6 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 8 0 0 8 8 0 0 8 0 0 8 0 8 0 0 % A
% Cys: 0 0 0 0 0 8 0 0 0 0 0 0 31 0 0 % C
% Asp: 0 0 0 8 54 0 0 0 0 16 0 0 0 93 8 % D
% Glu: 0 0 0 0 0 0 8 0 0 62 0 0 0 0 0 % E
% Phe: 0 0 0 8 0 0 0 0 8 0 0 16 0 0 8 % F
% Gly: 85 8 0 0 0 0 0 0 0 0 0 0 0 0 0 % G
% His: 0 0 0 0 8 0 8 0 0 0 0 8 0 0 0 % H
% Ile: 0 8 0 24 0 8 0 0 0 0 16 0 0 0 0 % I
% Lys: 0 0 0 0 16 0 0 0 0 0 0 0 8 0 0 % K
% Leu: 8 77 70 54 0 0 16 0 85 0 0 0 0 8 0 % L
% Met: 0 0 8 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 8 0 0 16 0 0 0 0 8 0 0 8 0 0 % N
% Pro: 0 0 0 0 0 8 0 0 0 8 0 0 0 0 0 % P
% Gln: 0 0 0 0 0 0 31 8 0 0 0 47 0 0 0 % Q
% Arg: 0 0 8 0 0 0 39 0 0 0 0 0 0 0 0 % R
% Ser: 0 0 8 0 0 8 0 0 0 8 8 8 31 0 0 % S
% Thr: 0 0 0 0 0 62 0 85 0 0 0 0 0 0 0 % T
% Val: 0 0 8 0 0 8 0 0 8 0 70 0 8 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 24 8 0 85 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _